Publication Library

Publication Library

Blockchain in a nutshell

Description: Blockchain enables a digital society where people can contribute, collaborate, and transact without having to second-guess trust and transparency. It is the technology behind the success of Bitcoin, Ethereum, and many disruptive applications and platforms that have positive impact in numerous sectors, including finance, education, health care, environment, transportation, and philanthropy, to name a few. This chapter provides a friendly description of essential concepts, mathematics, and algorithms that lay the foundation for blockchain technology.

Created At: 05 December 2024

Updated At: 05 December 2024

The Ethics of Advanced AI Assistants

Description: This paper focuses on the opportunities and the ethical and societal risks posed by advanced AI assistants. We define advanced AI assistants as artificial agents with natural language interfaces, whose function is to plan and execute sequences of actions on behalf of a user, across one or more domains, in line with the user's expectations. The paper starts by considering the technology itself, providing an overview of AI assistants, their technical foundations and potential range of applications. It then explores questions around AI value alignment, well-being, safety and malicious uses. Extending the circle of inquiry further, we next consider the relationship between advanced AI assistants and individual users in more detail, exploring topics such as manipulation and persuasion, anthropomorphism, appropriate relationships, trust and privacy. With this analysis in place, we consider the deployment of advanced assistants at a societal scale, focusing on cooperation, equity and access, misinformation, economic impact, the environment and how best to evaluate advanced AI assistants. Finally, we conclude by providing a range of recommendations for researchers, developers, policymakers and public stakeholders.

Created At: 05 December 2024

Updated At: 05 December 2024

Existential Conversations with Large Language Models Content, Community, and Culture

Description: Contemporary conversational AI systems based on large language models (LLMs) can engage users on a wide variety of topics, including philosophy, spirituality, and religion. Suitably prompted, LLMs can be coaxed into discussing such existentially significant matters as their own putative consciousness and the role of artificial intelligence in the fate of the Cosmos. Here we examine two lengthy conversations of this type. We trace likely sources, both ancient and modern, for the extensive repertoire of images, myths, metaphors, and conceptual esoterica that the language model draws on during these conversations, and foreground the contemporary communities and cultural movements that deploy related motifs, especially in their online activity. Finally, we consider the larger societal impacts of such engagements with LLMs.

Created At: 05 December 2024

Updated At: 05 December 2024

Data-Driven Analysis of AI in Medical Device Software in China Deep Learning and General AI Trends Based on Regulatory Data

Description: Artificial intelligence (AI) in medical device software (MDSW) represents a transformative clinical technology, attracting increasing attention within both the medical community and the regulators. In this study, we leverage a data-driven approach to automatically extract and analyze AI-enabled medical devices (AIMD) from the National Medical Products Administration (NMPA) regulatory database. The continued increase in publicly available regulatory data requires scalable methods for analysis. Automation of regulatory information screening is essential to create reproducible insights that can be quickly updated in an ever changing medical device landscape. More than 4 million entries were assessed, identifying 2,174 MDSW registrations, including 531 standalone applications and 1,643 integrated within medical devices, of which 43 were AI-enabled. It was shown that the leading medical specialties utilizing AIMD include respiratory (20.5%), ophthalmology/endocrinology (12.8%), and orthopedics (10.3%). This approach greatly improves the speed of data extracting providing a greater ability to compare and contrast. This study provides the first extensive, data-driven exploration of AIMD in China, showcasing the potential of automated regulatory data analysis in understanding and advancing the landscape of AI in medical technology.

Created At: 05 December 2024

Updated At: 05 December 2024

Uncovering Regulatory Affairs Complexity in Medical Products

Description: This study investigates the complexity of regulatory affairs in the medical device industry, a critical factor influencing market access and patient care. Through qualitative research, we sought expert insights to understand the factors contributing to this complexity. The study involved semi-structured interviews with 28 professionals from medical device companies, specializing in various aspects of regulatory affairs. These interviews were analyzed using open coding and Natural Language Processing (NLP) techniques. The findings reveal key sources of complexity within the regulatory landscape, divided into five domains: (A) Regulatory language complexity, (B) Intricacies within the regulatory process, (C) Global-level complexities, (D) Database-related considerations, and (E) Product-level issues. The participants highlighted the need for strategies to streamline regulatory compliance, enhance interactions between regulatory bodies and industry players, and develop adaptable frameworks for rapid technological advancements. Emphasizing interdisciplinary collaboration and increased transparency, the study concludes that these elements are vital for establishing coherent and effective regulatory procedures in the medical device sector.

Created At: 05 December 2024

Updated At: 05 December 2024

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